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Blog #3

Watching this ted talk it gave me so much inspiration on how she views life and her career. How she stated many factual things that not only happen in social work but in any careers or pathways in life. For example how she stated that life gets messy it’s just how life is. But instead of seeing in that point like many others do. She said well that makes me want to dig in that mess and make it work and unmask the messy for her. Viewing it differently to make it better or less harder in the long run. Which this is what I need to do in my stem career life. Not just say yes it’s hard and just deal with it. I can try to do many things to cut the edge off a bit to make it more workable. For example when focusing on an assignment I can research further then what I have gotten or even reach for help and opinions on other students or teachers.

Blog Post #1 2022

The way we view ourselves and our skills can have a significant impact on our life. In addition to the way we feel, the way we view our intellect and talents can have an impact on our performance, whether we cling to new habits, or if we gain new skills. As a person with a growth mindset, you believe in the ability to improve over time. As a result of having a fixed mindset, you may assume that you will never be good at something if you aren't good at it now.The way I have been before covid-19 was always a growth mindset. I always was engaged in learning a new path. I understood my abilities could be developed over time. I wouldn’t cheat or run from difficult problems or situations. I honestly didn’t know what anxiety and being scared to fail were at that time. I would want to say the environment I was in was healthy as well. Till my grandfather passes away, covid- 19 happened and everything went online. That’s when my fixed mindset hit hard. I felt so lost and useless that everyth...

Blog 4

Organization- Being organized makes everything else easier. It helps you get to work faster without wasting time looking for stuff. Keep your assignments and class information organized by subject. Put them in binders, notebooks, or folders. If you find yourself stuffing loose papers in your bag or grabbing different notebooks for the same class, it's time to stop and reorganize! Clean out your backpack regularly. Decide where to keep returned assignments and things you want to hold on to. Offload things you no longer need to carry around. Multitask- when I mean about multitasking, I mean about the amount of work you get during a short period of time which knocking down similar subjects together can have a good flow in getting assignments done. Work in stressful environments- when overload of work is due to be done working in a good pattern of spacing out assignments. Can still but a workload which working these stressful environments like taking a test or doing a lab re...

Blog post 3

There are many things on what i want to use my degree for and why.the goal is set diffrently its not only will i be making a finanical stable for myself but my family who immigrated here just 25 years ago.i wouldnt be able to make any oppurtities like these in senora mexico. i would want to use my degree to be able to give oppurtities to people who couldnt. Any way i can i feel like it doesnt just stop to just my degree but with what i do in the world that would help. i would open my own business just to help people who are in need for jobs or a foot in doors of industrties that are hard to get to.

Blog 2

we have successfully gotten into groups which got us to learn more information about slack. Slack is a messaging app for business that connects people to the information they need. By bringing people together to work as one unified team, Slack transforms the way organizations communicate. which in this group we have assign a project of peppers around the world as a fake project to kinda get a feel around this program. we assaigned tasks and contients to each member which we got to research information about the pepper that we had to get information from. Then that lead to all the information being in our messages and how we analyzed others new findings as well . Now we are on to linkedin which is Having a LinkedIn account as a student proves that you are dedicated to pursuing a career. By being specific in your summary and connecting with people in the field that you'd like to end up in, you prove that you're putting in the time and effort required to succeed in your chosen car...

Blog 1

An academic personal website takes you a step further in terms of increasing your visibility because it is an ideal place to showcase your complete research profile. You will attract attention to your publications, your name recognition will increase and you will get cited more. Moreover, a website is also useful for networking and collaborating with others, as well as for job searching and application. this week i got started on trying to set up a website. currently with the first weeks of school have been hectic. but now with classes and assignments balancing out. i am able to work more on my website.
To create the Tauntaun harvest data, we need to simulate the Tauntaun population through time. We’ll set up a 10 year population simulation, where we will track the number of male and female Tauntauns separately in each time step (each year). Tauntaun life history has been well studied by biologists on the icy planet of Hoth, and it’s reasonable to assume that life history characteristics are the same in Vermont. Individuals can begin breeding at the age of 1, and produce approximately 2 offspring per year. Individuals that are 0 years old are called “young” because they cannot breed. One-year-old breeders are called “recruits” because these individuals have been recruited into the breeding population. Tauntauns that survive the harvest and the natural mortality period are able to give advance to the birthday again. On the birthday, the animals that were 0 years old are now 1, and they instantly give birth to ~ 2 offspring. The animals that were 1 years old are now 2, and they in...

CHAPTER 9

To get you started, we'll go through four popular statistical tests: chi-squared, t-test, correlation, and regression, as well as a method for extracting the data you need. My new Tauntaun dataset must be loaded into R for all of the analyses in this exercise. . Remember that we're working with data that has been "super-cleaned, combined, etc." and is saved as an.RDS file.Our first test, the chi-squared test, is a straightforward method for analyzing categorical results with any number of categories. For example, you can use this test to see if Tauntaun fur length (short, medium, long) and fur color (grey, white) are related (or dependent) on one another. That is to say, the probability of a specific Tauntaun fur color depends on the length of its fur; and vice versa, the likelihood of a particular fur color depends on the length of its fur.Now, the purpose of the chi-squared test is to determine if gender and party are INDEPENDENT of each other. The chi-squared test ...

CHAPTER 7 AND 8

the clean harvest The first Rdata file contains information about all the Tauntauns that have been harvested, while the second contains information about the hunters. A similar column in both datasets, hunter.id, identifies who harvested which animal.A column named hunter.id appears in both datasets, and it is the unique number that identifies each hunter. We'll use the merge feature to combine these two data frames into a single data frame.A "left join" (lower left example) will hold all records in the left table and only those in the right table where the left table matches. NA is used to fill in any missing values. A "right join" (lower right example) will hold all records in the right table and only those in the left table where the right table matches.If we use the order function, we can filter by multiple columns. Each additional sort vector is entered as an argument of the order function, separated by commas. The order function returns a vector of indices...

CHAPTER 5 AND 6

The final object type we'll discuss is a data frame, which is a collection of vectors with the same length. In R, data frames are used to store most datasets, and we'll get a lot of experience with them in the following chapters. Let's put the three vectors, fiveIntegers, fiveBooleans, and fiveRandoms, into a data frame with the data for now. role of the frame.We'll start a new project named Tauntauns here. This project will house all of the materials related to our Tauntaun population study.An absolute file path contains your computer’s root directory and all other subdirectories that contain a file or folder. In Windows the root directory is usually the C drive; in linux and MacOS it begins with a forward slash / or tilde ~. A relative file path locates your file relative to your working directory, which should be your Tauntaun project directory (one of the benefits of using projects is that the working directory is automatically set upon opening).The backslash key is...

CHAPTER 4

All artifacts we make must be stored somewhere in R. The global environment is home to our artifacts, fiveNumbers, outcome, and lowNumbers. Package functions are all contained within their own package environment.This function takes four arguments: x is the vector to sample from, size is the number of samples to take, replace is what you want to sample with replacement (which means the same numbers can be drawn repeatedly), and prob is used to weight your samples such that some have a better probability of being chosen than others.One of the most common coding errors in R, in our experience, is attempting to execute a function on objects of a given class when R is expecting something else. When it comes to R functions, the str function is one of your best friends; it gives you not only the class but also a look at the values.A vector is a single data row or column. The cells A1:A3 are illuminated, and this group of cells is labeled mixed (see the upper left of the figure). This specifi...

CHAPTER 3

This portion should not be overlooked. The purpose of a helpfile's Examples section is to provide example code that demonstrates how to use a function, beginning with the development of some sample data and then demonstrating how to use the function on the sample data. By copying and pasting the code into the Console and then submitting it, you will learn a lot.We generated an object called “xx” in line 1 of this code, which has the integers -9 to 9 in 1 increments. Another way to make a sequence in R is to use the colon operator (:). Simply type xx and submit it to the R console if you want to look at it.This code, starting on line 2, is typical R helpfile code, which nests many functions together in a short, concise code. Expert coders tend to keep their code as short as possible... it's succinct, simple to understand, and everyone else who uses it won't have to wade through many lines of code to get to the result. As long as you aren't a fledgling, all of this is per...

CHAPTER 2

We'll take a short tour of RStudio in this chapter. we will be writing the first R script along the way. The RStudio developers have excellent documentation on their website, which you can explore at your leisure. Rather than going over each and every choice, the aim here is to give us a broad overview. You can build new folders (directories) on the Files tab.You can also rename, erase, and transfer files on your computer. You can navigate to any location on your device using RStudio. When running in R, the program needs to know where to look for inputs and outputs, so it will look in a directory called a "working directory" first. The getwd feature, which can be entered in your console or in your script, can be used to locate your working directory.R suggests that you use the double question mark technique, which will be??meatloaf, since there is no documentation for meatloaf. A keyword search is launched as a result of this. The double question mark is simply a feat...

Assignment one

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hello my name is kathy serrano this week we have been using data visualization with R. we have been given a pdf book to guide us into new knowledge of data visualization which was writteb by rob kabacoff first start this assaigment was setting up and downlading datacamp and other prequisites to start. starting off with chapter one we talk about data basics. how data frames and tinnles are r structures for storing tabulat data. we look at the contents of a data frame or tibble. we open a help page that describes a data frame or tibble and we also identify varibles and their types in a tible. i learned that mpg abf flights dataset appear more frequently in r examples. tibkes are data frames but they are tweaked some older behaviours to make it a little easier. r is an old language and it is difficult to change base r without breakinf exisiting code so most innovation occurs in packages. i also learned the five key dplyr functions which allow to slove vast majority of data manipul...
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Today I worked on assignment 11 of the protein bioinformatics project I was able to get information from the website and data provided ID: PIR_HUMAN DESCRIPTION: RecName: Full=Pirin; EC=1.13.11.24; AltName: Full=Probable quercetin 2,3-dioxygenase PIR; Short=Probable quercetinase; FUNCTION: Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro). CATALYTIC ACTIVITY: Quercetin + O(2) = 2-(3,4- dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H(+). COFACTOR: Binds 1 iron ion per subunit. ENZYME REGULATION: Inhibited by kojic acid, sodium diethyldithiocarbamate and 1,10-phenanthroline monohydrochloride. PATHWAY: Flavonoid metabolism; quercetin degradation. SUBUNIT: May interact wi...

ten

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Today I worked on assignment ten of the protein bioinformatics project I was able to get information from the website and data provided Description: Homo sapiens pirin (PIR), transcript variant 2, mRNA. (from RefSeq NM_001018109) RefSeq Summary (NM_001018109): This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000380420.10 Gencode Gene: ENSG00000087842.11 An ORegAnno record describes an experimentally proven and published regulatory region (promoter, en...
Today I worked on assignment nine of the protein bioinformatics project I was able to get information from the website and data provided Gene: PIR Description: Homo sapiens pirin (PIR), transcript variant 1, mRNA. (from RefSeq NM_003662) Ensembl gene ID: ENSG00000087842.6 GENCODE biotype: protein_coding Gene class: coding Highest median expression: 16.80 RPKM in Bladder Total median expression: 281.69 RPKM Score: 407 Genomic position: hg38 chrX:15384799-15493564 The NIH Genotype-Tissue Expression (GTEx) project was created to establish a sample and data resource for studies on the relationship between genetic variation and gene expression in multiple human tissues. This track shows median gene expression levels in 52 tissues and 2 cell lines, based on RNA-seq data from the GTEx final data release (V8, August 2019). This release is based on data from 17,382 tissue samples obtained from 948 adult post-mortem individuals. The scientific goal of the GTEx project required that the dono...
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Today I worked on assignment eight of the protein bioinformatics project I was able to get information from the website and data provided Gene: PIR Description: Homo sapiens pirin (PIR), transcript variant 1, mRNA. (from RefSeq NM_003662) Ensembl gene ID: ENSG00000087842.6 GENCODE biotype: protein_coding Gene class: coding Highest median expression: 16.80 RPKM in Bladder Total median expression: 281.69 RPKM Score: 407 Genomic position: hg38 chrX:15384799-15493564 The bargraph display has the same width and tissue order for all genes. Mouse hover over a bar will show the tissue and median expression level. The Squish display mode draws a rectangle for each gene, colored to indicate the tissue with highest expression level if it contributes more than 10% to the overall expression (and colored black if no tissue predominates). In Dense mode, the darkness of the grayscale rectangle displayed for the gene reflects the total median expression level across all tissues. Credits Statis...
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  Kathy serrano   Protein:  UniProt:O 00625 PIR (1x)   Today I worked on assignment six of the protein bioinformatics project I was able to get information from the website and data provided     Pirin   Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for effici ent terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity Tissue:  Highly expressed in a subset of melanomas. Detected at very low levels in most tissues (at protein level). Expressed in all tissues, with the highest level of expres sion in the heart and liver. there was not much I can fin on the website provided viewed no disease. 1. Protein:   O00625  -  Pir in  [Gene:  PIR ]   UniProt id:   PIR _HUMAN Protein:   Pir in Gene:   PIR
  Kathy serrano   Protein:  UniProt:O 00625 PIR (1x)   Today I worked on assignment five of the protein bioinformatics project I was able to get information from the website and data provided     Pirin   Pathway   Flavonoid metabolism; quercetin degradation.   Subcellular Location   Nucleus. Cytoplasm. Note=Predominantly localized in dot-like subnuclear structures. Cytoplasmic localization of PIR seems to positively correlate with melanoma progression.   Function   Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro).   GO Cellular Component   cytoplasm; cytosol; nucleoplasm; (1 more)   GO Molecular Function   metal ion binding; quercetin 2,3-dioxygenase activity; transcription coreg...