Kathy serrano Protein: UniProt:O 00625 PIR (1x) Today I worked on assignment four of the protein bioinformatics project I was able to get information from the website and data provided SPIRE1 Protein spire homolog 1 Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:11747823, PubMed:21620703). Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (PubMed:11747823). Required for asymmetric spindle positioning and asymmetric cell division during meiosis (PubMed:21620703). Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (PubMed:21620703). Also acts in the nucleus: together with FMN2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and re...
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Assignment two
Today I worked on assignment two of the protein bioinformatics project I was able to get information on my assigned protein Pirin o00625 and began to gather information. the summary about the conserved domain of pirin: Pirin : Pirin This family consists of Pirin proteins from both eukaryotes and prokaryotes. The function of Pirin i... Accession: pfam02678 ID: 367141 View in Cn3D Specific Protein Protein Superfamily Superfamily Members PubMed Select item 389752 2. cupin_like: Conserved domain found in cupin and related proteins A diverse protein domains superfamily which includes both metal-dependent and metal-independent enzy... Accession: cl21464 ID: 389752 View in Cn3D Protein Superfamily Members PubMed Select item 380445 3. cupin_Yhhw_C: Escherichia coli YhhW and YhaK and related proteins, pirin -like bicupin, C-terminal cupin domain This family includes the C-terminal domain of YhhW and YhaK, Esc...
assignment one
September 7 2020 Kathy Serrano Today I worked on assignment one of the protein bioinformatics project I was able to get information on my assigned protein Pirin o00625 and began to gather information. My protein function transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). Tissue specify Highly expressed in a subset of melanomas. Detected at very low levels in most tissues (at protein level). Expressed in all tissues, with highest level of expression in heart and liver. Belongs to pirin family, Genetic variations in PIR might have a sex-specific influence on bone mineral density differences in some populations. My protein is 90% related to RHIBE ( Rhinopithecus bieti ) which another name for is Black ...