Kathy serrano 

Protein: UniProt:O00625 PIR (1x) 

Today I worked on assignment four of the protein bioinformatics project I was able to get information from the website and data provided 

 

SPIRE1 

Protein spire homolog 1 

 

Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:11747823, PubMed:21620703). Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (PubMed:11747823). Required for asymmetric spindle positioning and asymmetric cell division during meiosis (PubMed:21620703). Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (PubMed:21620703). Also acts in the nucleus: together with FMN2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (PubMed:26287480). 

Results from https://string-db.org/cgi/network.pl 

- PIR - Pirin; Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro); Belongs to the pirin family 

Comments

Post a Comment

Popular posts from this blog

To create the Tauntaun harvest data, we need to simulate the Tauntaun population through time. We’ll set up a 10 year population simulation, where we will track the number of male and female Tauntauns separately in each time step (each year). Tauntaun life history has been well studied by biologists on the icy planet of Hoth, and it’s reasonable to assume that life history characteristics are the same in Vermont. Individuals can begin breeding at the age of 1, and produce approximately 2 offspring per year. Individuals that are 0 years old are called “young” because they cannot breed. One-year-old breeders are called “recruits” because these individuals have been recruited into the breeding population. Tauntauns that survive the harvest and the natural mortality period are able to give advance to the birthday again. On the birthday, the animals that were 0 years old are now 1, and they instantly give birth to ~ 2 offspring. The animals that were 1 years old are now 2, and they in...
Read more

Blog 1

An academic personal website takes you a step further in terms of increasing your visibility because it is an ideal place to showcase your complete research profile. You will attract attention to your publications, your name recognition will increase and you will get cited more. Moreover, a website is also useful for networking and collaborating with others, as well as for job searching and application. this week i got started on trying to set up a website. currently with the first weeks of school have been hectic. but now with classes and assignments balancing out. i am able to work more on my website.
Read more

Blog post 3

There are many things on what i want to use my degree for and why.the goal is set diffrently its not only will i be making a finanical stable for myself but my family who immigrated here just 25 years ago.i wouldnt be able to make any oppurtities like these in senora mexico. i would want to use my degree to be able to give oppurtities to people who couldnt. Any way i can i feel like it doesnt just stop to just my degree but with what i do in the world that would help. i would open my own business just to help people who are in need for jobs or a foot in doors of industrties that are hard to get to.
Read more